| Chemical Specifications | |
|---|---|
| Product Name | AICAR (Acadesine) |
| CAS Number | 2627-69-2 |
| Molecular Formula | C9H14N4O5 |
| Molecular Weight | 258.23 g/mol |
| Purity (HPLC) | ≥ 99.0% |
| Appearance | White Lyophilized Powder |
| Storage | Store at -20°C (Protect from light and moisture) |
What is AICAR?
AICAR (Acadesine), supplied in a premium 50mg x 10 Vials research kit, is a potent cell-permeable analog of Adenosine Monophosphate (AMP). It is globally recognized in metabolic and endurance research as a master **AMPK Activator**. AICAR’s unique biochemical profile allows it to effectively trick muscle cells into believing they are under a state of extreme energetic stress, mimicking the metabolic effects of prolonged, exhaustive exercise. This “exercise in a bottle” mechanism makes it an unprecedented tool for studying mitochondrial biogenesis, extreme fat oxidation, and maximal endurance enhancement without the actual requirement of physical exertion.
Key Features & Research Benefits
Direct AMPK Activation
Functions as a master metabolic switch. It directly binds to and activates the enzyme AMPK (AMP-activated protein kinase), effectively re-programming the cell’s energy sensor to prioritize survival and endurance pathways.
Extreme Endurance Boost
By mimicking exhausting exercise signals, it drastically enhances the muscle’s ability to maintain prolonged exertion. Research models demonstrate substantial increases in running time and distance to fatigue.
Accelerated Fat Oxidation
Forcefully shifts metabolism towards lipid usage. It tells the body to oxidize stored fatty acids at an accelerated rate for energy, promoting fat burning even in a non-exercising state.
Mitochondrial Biogenesis
Instructs muscle cells to build more mitochondria—the “power plants” of the cell. More mitochondria directly correlate with vastly improved cellular energy efficiency and explosive muscular power potential.
Enhanced Recovery Signaling
By optimizing glucose uptake and reducing lactic acid accumulation markers in sensitive tissues, AICAR provides a vital pathway for studying reduced muscle fatigue and accelerated recovery times.
Verified High Dose & Purity
Each 10-vial kit provides a substantial total of 500mg (50mg/vial) of ≥99.0% purified (HPLC) lyophilized AICAR powder, ensuring maximum dosage precision and batch-to-batch consistency for critical longitudinal metabolic research.
How It Works: “Exercise in a Bottle”
AICAR (Acadesine) operates as the ultimate metabolic hack, directly hijacking the cellular energy sensing mechanism. The central dogma of cellular energy states that the enzyme AMP-activated protein kinase (AMPK) acts as the cellular master regulator.
When you perform long, gruelling有氧训练, your muscle cells burn through their energy supply (ATP), converting it to AMP. The cell, sensing this massive deficit of energy (high AMP), activates AMPK to flip a metabolic switch from energy storage to survival-based energy production. However, performing this level of exhaustive exercise is physically damaging and time-consuming.
AICAR changes everything. Because it is a cell-permeable analog of AMP, AICAR is absorbed directly into the muscle cells, where it is converted into a substance that is almost chemically identical to AMP. This fools the AMPK enzyme entirely. The enzyme “sees” a huge influx of what it thinks is AMP and mistakenly believes the cell is in a state of catastrophic energy stress—as if the individual has already run 30 kilometers—even if they are perfectly at rest.
In response, AMPK unleashes a powerful synergistic cascade of physiological changes: it forcefully increases glucose uptake, rapidly accelerates fatty acid oxidation (the direct conversion of stored fat into energy), and triggers mitochondrial biogenesis (the creation of new cellular power plants). By simulating the grueling results of elite training without the physical exertion, AICAR provides researchers with the definitive cell-signaling cheat code for investigating metabolic optimization.
🧪 What’s In The Kit
- Active Compound: AICAR (Acadesine / 5-Aminoimidazole-4-carboxamide ribonucleotide)
- Format: 10-Vial Research Kit
- State: Sterile, Lyophilized Powder
- Net Contents: 50mg per vial (500mg total)
- Purity: ≥99.0% (HPLC Verified)
👩🔬 Who Uses It
- Endurance & Sports Science Labs
- Obesity & Lipid Metabolism Researchers
- Cardiovascular Health Investigators
- Mitochondrial Dysfunction Specialists
- Hormone & Doping Control Authorities (as a reference standard)
🔗 Best Paired With
- Sterile Bacteriostatic Water (BAC)
- Precision Laboratory Pipettes
- GW501516 (Cardarine) (Classic Synergistic Pairing)
- HGH / IGF-1 (Cellular Growth Studies)
- Vial Storage Organizers (-20°C)
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